TY - BOOK AU - Tozer,Thomas N. AU - Rowland,Malcolm TI - Essentials of pharmacokinetics and pharmacodynamics SN - 9781451194425 (pbk) AV - RM301.5 .T93 2016 U1 - 615/.7 23 PY - 2016///] CY - Philadelphia PB - Wolters Kluwer KW - Pharmacokinetics KW - Dose-Response Relationship, Drug KW - Drug Therapy KW - methods KW - Pharmaceutical Preparations KW - administration & dosage N1 - Preceded by Introduction to pharmacokinetics and pharmacodynamics : the quantitative basis of drug therapy / Thomas N. Tozer, Malcolm Rowland. c2006; Includes index; Input-exposure relationships -- Exposure-response relationships -- Membranes : a determining factor -- Quantifying events following an intravenous bolus -- Physiologic and physicochemical determinants of distribution and elimination -- Quantifying events following an extravascular dose -- Physiologic and physicochemical determinants of drug absorption -- Response following a single dose -- Therapeutic window -- Constant-rate regimens -- Multiple-dose regimens -- Variability -- Initiating and managing therapy ER -