000 02054cam a2200421 i 4500
999 _c12002
_d12002
001 18650396
003 OSt
005 20180504114022.0
008 150601s2016 paua 001 0 eng
010 _a 2015021592
020 _a9781451194425 (pbk)
035 _a(DNLM)101659988
040 _aDNLM/DLC
_cDLC
_erda
_dDLC
042 _apcc
050 0 0 _aRM301.5
_b.T93 2016
060 1 0 _aQV 38
082 0 0 _a615/.7
_223
100 1 _aTozer, Thomas N.,
_eauthor.
_923799
240 1 0 _aIntroduction to pharmacokinetics and pharmacodynamics
245 1 0 _aEssentials of pharmacokinetics and pharmacodynamics /
_cThomas N. Tozer, Malcolm Rowland.
250 _aSecond edition.
264 1 _aPhiladelphia :
_bWolters Kluwer,
_c[2016]
300 _axii, 386 pages :
_billustrations ;
_c26 cm
336 _atext
_2rdacontent
337 _aunmediated
_2rdamedia
338 _avolume
_2rdacarrier
500 _aPreceded by Introduction to pharmacokinetics and pharmacodynamics : the quantitative basis of drug therapy / Thomas N. Tozer, Malcolm Rowland. c2006.
500 _aIncludes index.
505 0 _aInput-exposure relationships -- Exposure-response relationships -- Membranes : a determining factor -- Quantifying events following an intravenous bolus -- Physiologic and physicochemical determinants of distribution and elimination -- Quantifying events following an extravascular dose -- Physiologic and physicochemical determinants of drug absorption -- Response following a single dose -- Therapeutic window -- Constant-rate regimens -- Multiple-dose regimens -- Variability -- Initiating and managing therapy.
650 1 2 _aPharmacokinetics.
_923800
650 2 2 _aDose-Response Relationship, Drug.
_923801
650 2 2 _aDrug Therapy
_xmethods.
_923802
650 2 2 _aPharmaceutical Preparations
_xadministration & dosage.
_923803
700 1 _aRowland, Malcolm,
_eauthor.
_92047
906 _a7
_bcbc
_corignew
_d1
_eecip
_f20
_gy-gencatlg
942 _2ddc
_cEB