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001 | 1729286 | ||
003 | OSt | ||
005 | 20200403130445.0 | ||
007 | cr|cn |||||||| | ||
008 | 171004t20192019ne a b 001 0 eng | ||
020 | _a9780702068966 | ||
020 | _a0702068969 | ||
020 | _a9780702070396 (eISBN) | ||
035 |
_a(OCoLC)1034989510 _z(OCoLC)1005105355 |
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040 |
_aAU@ _beng _erda _cAU@ _dOCLCO _dYDX _dBDX _dCDX _dVAM _dIAX |
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041 | 0 | 9 | _aeng |
042 | _apcc | ||
050 | 4 |
_aRC582 _b.C549 2019 |
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060 | 0 | 0 | _a2018 E-694 |
060 | 1 | 0 | _aQW 504 |
082 | 0 | 4 |
_a616.07/9 _223 |
130 | 0 |
_aClinical immunology (Rich) _935825 |
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245 | 1 | 0 |
_aClinical immunology : _bprinciples and practice / _cedited by Robert Rich, MD [and five others]. |
250 | _aFifth edition. | ||
264 | 1 |
_a[Amsterdam] : _bElsevier, _c2019. |
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264 | 4 | _c©2019. | |
300 |
_axviii, 1373 pages : _billustrations (chiefly color) ; _c29 cm. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_aunmediated _bn _2rdamedia |
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338 |
_avolume _bnc _2rdacarrier |
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504 | _aIncludes bibliographical references and index. | ||
505 | 0 | _aSection 1: Principles of immune response. The human immune response -- Organization of the immune system -- Innate immunity -- Antigen receptor genes, gene products, and co-receptors -- The major histocompatibility complex -- Antigens and antigen presentation -- B-cell development and differentiation -- T-cell development -- Cytokines and cytokine receptors -- Chemokines and chemokine receptors -- Lymphocyte adhesion and trafficking -- T-cell activation and tolerance -- Regulated cell death -- The microbiota in immunity and inflammation -- Section 2: Host defense mechanisms and inflammation. Immunoglobulin function -- Helper T-cell subsets and control of the inflammatory response -- Cytotoxic T lymphocytes and natural killer cells -- Regulatory immune cells -- Host defenses in the skin -- Host defenses at mucosal surfaces -- Complement in host deficiencies and diseases -- Phagocyte deficiencies -- Mast cells, basophils, and mastocytosis -- Eosinophils and eosinophilia -- Section 3: Host defenses to infectious agents. Host defenses to viruses -- Host defenses to intracellular bacteria -- Host defenses to extracellular bacteria -- Host defenses to spirochetes -- Host defenses to fungi -- Host defenses to protozoa -- Host defenses to helminths -- Section 4: Immunologic deficiencies. Approach to the evaluation of the immunodeficient patient -- Human genomics in immunology -- Primary antibody deficiencies -- Primary T-cell immunodeficiencies -- Immunodeficiencies at the interface of innate and adaptive immunity -- Infections in the immunocompromised host -- Immune deficiencies at the extremes of age -- HIV infection and acquired immunodeficiency syndrome -- Autoantibody mediated phenocopies of primary immunodeficiency diseases -- Section 5: Allergic diseases. Immunological mechanisms of airway diseases and pathways to therapy -- Urticaria, angioedema, and anaphylaxis -- Allergic reactions to stinging and biting insects -- Atopic and contact dermatitis -- Food allergy -- Eosinophil-associated gastrointestinal disorders -- Allergic disorders of the eye -- Drug hypersensitivity -- Occupational respiratory allergies -- | |
505 | 0 | _aSection 6: Systemic immune diseases. Mechanisms of autoimmunity -- Systemic lupus erythematosus -- Rheumatoid arthritis -- Juvenile idiopathic arthritis -- Sjögren's syndrome -- Scleroderma-systemic sclerosis -- Inflammatory muscle diseases -- Spondyloarthritis -- Small and medium vessel primary vasculitis -- Large-vessel vasculitides -- Systemic autoinflammatory syndromes -- Antiphospholipid syndrome -- Section 7: Organ-specific inflammatory disease. Immunohematologic disorders -- Bullous diseases of the skin and mucous membranes -- Immunology of psoriasis -- Myasthenia gravis -- Multiple sclerosis -- Autoimmune peripheral neuropathies -- Immunologic renal diseases -- Inflammation and atherothrombosis -- Autoimmune thyroid diseases -- Diabetes and related autoimmune diseases -- Immunologic lung diseases -- Sarcoidosis -- Immunologic ocular disease -- Immunologic diseases of the gastrointestinal tract -- Inflammatory hepatobiliary diseases -- Section 8: Immunology of neoplasia. Tumor immunotherapy -- Lymphoid leukemias -- Lymphomas -- Monoclonal gammopathies -- Section 9: Transplantation. Concepts and challenges in organ transplantation: rejection, immunosuppression, and tolerance -- Immune reconstitution therapy for immunodeficiency -- Hematopoietic stem cell transplantation for malignant diseases -- Section 10: Prevention and therapy of immunologic diseases. Immunoglobulin therapy: replacement and immunomodulation -- Gene therapy -- Glucocorticoids -- Immunomodulating pharmaceuticals -- Protein kinase antagonists as therapeutic agents for immunological and inflammatory disorders -- Biological modifiers of inflammation -- Vaccines -- Immunotherapy of allergic disease -- Section 11: Diagnostic immunology. Flow cytometry -- Assessment of functional immune responses -- Assessment of neutrophil function -- Assessment of human allergic diseases -- Molecular methods -- Appendices. Selected CD molecules and their characteristics -- Laboratory reference values -- Vaccine schedules. | |
530 | _aAlso issued online | ||
546 | _aenglish | ||
650 | 1 | 2 |
_aImmune System _xphysiology _0https://id.nlm.nih.gov/mesh/D007107Q000502 _9106 |
650 | 2 | 2 |
_aImmune System Diseases _ximmunology _0https://id.nlm.nih.gov/mesh/D007154Q000276 _9106 |
650 | 2 | 2 |
_aImmunity _xphysiology _0https://id.nlm.nih.gov/mesh/D007109Q000502 _935826 |
700 | 1 |
_aRich, Robert R., _eeditor. _922675 |
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856 | 4 |
_uhttp://online.fliphtml5.com/lluzx/lqsm/ _zцахимаар унших |
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942 |
_2ddc _cEB |
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998 | _b20190325 |