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008 171004t20192019ne a b 001 0 eng
020 _a9780702068966
020 _a0702068969
020 _a9780702070396 (eISBN)
035 _a(OCoLC)1034989510
_z(OCoLC)1005105355
040 _aAU@
_beng
_erda
_cAU@
_dOCLCO
_dYDX
_dBDX
_dCDX
_dVAM
_dIAX
041 0 9 _aeng
042 _apcc
050 4 _aRC582
_b.C549 2019
060 0 0 _a2018 E-694
060 1 0 _aQW 504
082 0 4 _a616.07/9
_223
130 0 _aClinical immunology (Rich)
_935825
245 1 0 _aClinical immunology :
_bprinciples and practice /
_cedited by Robert Rich, MD [and five others].
250 _aFifth edition.
264 1 _a[Amsterdam] :
_bElsevier,
_c2019.
264 4 _c©2019.
300 _axviii, 1373 pages :
_billustrations (chiefly color) ;
_c29 cm.
336 _atext
_btxt
_2rdacontent
337 _aunmediated
_bn
_2rdamedia
338 _avolume
_bnc
_2rdacarrier
504 _aIncludes bibliographical references and index.
505 0 _aSection 1: Principles of immune response. The human immune response -- Organization of the immune system -- Innate immunity -- Antigen receptor genes, gene products, and co-receptors -- The major histocompatibility complex -- Antigens and antigen presentation -- B-cell development and differentiation -- T-cell development -- Cytokines and cytokine receptors -- Chemokines and chemokine receptors -- Lymphocyte adhesion and trafficking -- T-cell activation and tolerance -- Regulated cell death -- The microbiota in immunity and inflammation -- Section 2: Host defense mechanisms and inflammation. Immunoglobulin function -- Helper T-cell subsets and control of the inflammatory response -- Cytotoxic T lymphocytes and natural killer cells -- Regulatory immune cells -- Host defenses in the skin -- Host defenses at mucosal surfaces -- Complement in host deficiencies and diseases -- Phagocyte deficiencies -- Mast cells, basophils, and mastocytosis -- Eosinophils and eosinophilia -- Section 3: Host defenses to infectious agents. Host defenses to viruses -- Host defenses to intracellular bacteria -- Host defenses to extracellular bacteria -- Host defenses to spirochetes -- Host defenses to fungi -- Host defenses to protozoa -- Host defenses to helminths -- Section 4: Immunologic deficiencies. Approach to the evaluation of the immunodeficient patient -- Human genomics in immunology -- Primary antibody deficiencies -- Primary T-cell immunodeficiencies -- Immunodeficiencies at the interface of innate and adaptive immunity -- Infections in the immunocompromised host -- Immune deficiencies at the extremes of age -- HIV infection and acquired immunodeficiency syndrome -- Autoantibody mediated phenocopies of primary immunodeficiency diseases -- Section 5: Allergic diseases. Immunological mechanisms of airway diseases and pathways to therapy -- Urticaria, angioedema, and anaphylaxis -- Allergic reactions to stinging and biting insects -- Atopic and contact dermatitis -- Food allergy -- Eosinophil-associated gastrointestinal disorders -- Allergic disorders of the eye -- Drug hypersensitivity -- Occupational respiratory allergies --
505 0 _aSection 6: Systemic immune diseases. Mechanisms of autoimmunity -- Systemic lupus erythematosus -- Rheumatoid arthritis -- Juvenile idiopathic arthritis -- Sjögren's syndrome -- Scleroderma-systemic sclerosis -- Inflammatory muscle diseases -- Spondyloarthritis -- Small and medium vessel primary vasculitis -- Large-vessel vasculitides -- Systemic autoinflammatory syndromes -- Antiphospholipid syndrome -- Section 7: Organ-specific inflammatory disease. Immunohematologic disorders -- Bullous diseases of the skin and mucous membranes -- Immunology of psoriasis -- Myasthenia gravis -- Multiple sclerosis -- Autoimmune peripheral neuropathies -- Immunologic renal diseases -- Inflammation and atherothrombosis -- Autoimmune thyroid diseases -- Diabetes and related autoimmune diseases -- Immunologic lung diseases -- Sarcoidosis -- Immunologic ocular disease -- Immunologic diseases of the gastrointestinal tract -- Inflammatory hepatobiliary diseases -- Section 8: Immunology of neoplasia. Tumor immunotherapy -- Lymphoid leukemias -- Lymphomas -- Monoclonal gammopathies -- Section 9: Transplantation. Concepts and challenges in organ transplantation: rejection, immunosuppression, and tolerance -- Immune reconstitution therapy for immunodeficiency -- Hematopoietic stem cell transplantation for malignant diseases -- Section 10: Prevention and therapy of immunologic diseases. Immunoglobulin therapy: replacement and immunomodulation -- Gene therapy -- Glucocorticoids -- Immunomodulating pharmaceuticals -- Protein kinase antagonists as therapeutic agents for immunological and inflammatory disorders -- Biological modifiers of inflammation -- Vaccines -- Immunotherapy of allergic disease -- Section 11: Diagnostic immunology. Flow cytometry -- Assessment of functional immune responses -- Assessment of neutrophil function -- Assessment of human allergic diseases -- Molecular methods -- Appendices. Selected CD molecules and their characteristics -- Laboratory reference values -- Vaccine schedules.
530 _aAlso issued online
546 _aenglish
650 1 2 _aImmune System
_xphysiology
_0https://id.nlm.nih.gov/mesh/D007107Q000502
_9106
650 2 2 _aImmune System Diseases
_ximmunology
_0https://id.nlm.nih.gov/mesh/D007154Q000276
_9106
650 2 2 _aImmunity
_xphysiology
_0https://id.nlm.nih.gov/mesh/D007109Q000502
_935826
700 1 _aRich, Robert R.,
_eeditor.
_922675
856 4 _uhttp://online.fliphtml5.com/lluzx/lqsm/
_zцахимаар унших
942 _2ddc
_cEB
998 _b20190325