000 04281nam a22005655i 4500
001 021251145
003 UkOxU
005 20200523121710.0
006 m o d
007 cr nn 008mamaa
008 170602s2017 gw | o |||| 0|eng d
020 _a9783319540641
024 7 _a10.1007/978-3-319-54064-1
_2doi
035 _a(DE-He213)978-3-319-54064-1
040 _aАнагаах ухааны төв номын сан
050 4 _aQH359-425
072 7 _aPSAJ
_2bicssc
072 7 _aSCI027000
_2bisacsh
082 0 4 _a576.8
_223
100 1 _aBleidorn, Christoph,
_eauthor.
_939702
245 1 0 _aPhylogenomics :
_bAn Introduction /
_cby Christoph Bleidorn.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2017.
300 _a1 online resource (XIII, 222 p.) :
_b89 illus., 87 illus. in color.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
500 _aOnline access provided by SpringerLink.
505 0 _a1. Genomes -- 01.1 Prokaryotes vs. Eukaryotes -- 01.2 Genome Structure -- 01.3 Genome Sizes -- 01.4 Human Genome and Ancient DNA (Neandertaler, Denisova) -- 2. Genomes of Organelles -- 02.1 Mitochondria -- 02.2 Plastids -- 02.3 Outlook Obligate Endosymbionts -- 3. Transcriptomes -- 03.1 mRNA -- 03.2 Transcripts -- 03.3 Expression Level -- 03.4 Alternative Splicing -- 4. Sequencing Techniques -- 04.1 Sanger -- 04.2 Illumina -- 04.3 454 -- 04.4 PacBio -- 04.5 Outlook Nanopore Sequencing -- 5. Genome Sequencing Strategies -- 05.1 Whole Genome Shotgun -- 05.2 RADseq -- 05.3 Target Enrichment -- 05.4 RNAseq -- 6. Assembly and Mapping -- 06.1 Assembling Strategies (kmer vs OLC) -- 06.2 Data Quality and Filtering -- 06.3 Re-Sequencing and Mapping -- 06.4 De novo Assembly Genome -- 06.5 De novo Assembly Transcriptome -- 7. Locating Genes -- 07.1 Orthology vs. Paralogy -- 07.2 BLAST and Successors -- 07.3 Hidden Markov Profile -- 07.4 Ortholog Conjecture -- 8. Alignment -- 08.1 Alignment Strategies -- 08.2 Alignment Masking -- 9. Phylogenetic Analysis -- 09.1 Distance Measurements -- 09.2 Maximum Parsimony -- 09.3 Maximum Likelihood -- 09.4 Bayesian Inference -- 09.5 Supermatrix vs. Single Gene Analysis (Gene Trees vs. Species Trees) -- 10. Systematic Errors in phylogenetic Analysis -- 10.1 Prediction: Evolutionary Models -- 10.2 Heterogenity Nucleotide/Amino Acid-Composition -- 10.3 Variation of substitution rate between the lines -- 10.4 Variation of substitution rate over time -- 10.5 New Approaches to Correct systematic Errors -- 11. Genome-wide Characteristics -- 11.1 Gene Order -- 11.2 Mobile Elements -- 11.3 microRNAs -- 11.4 Differences in the genetic code -- 12. Index -- 13. References.
520 _aThis unique textbook provides a clear and concise overview of the key principles of the complex field of phylogenomics, with a particular focus on sequencing technologies that are crucial to studying and understanding interrelations in evolutionary genomics. It includes chapters dedicated to the analysis of nucleotide sequences using assembling and alignment methods and also discusses the main strategies for phylogenetic studies, systematic errors and their correction. This highly readable textbook is intended for graduate students and young researchers with an interest in phylogenetics and evolutionary developmental biology.
546 _aEnglish
588 _aDescription based on Springer metadata.
650 0 _aLife sciences.
_939703
650 0 _aHuman genetics.
_939704
650 0 _aBioinformatics.
_92365
650 0 _aEvolution (Biology)
_939705
650 0 _aMicrobial genetics.
_939706
650 0 _aMicrobial genomics.
_939707
650 0 _aAnimal genetics.
_939708
650 1 4 _aLife Sciences.
_939709
650 2 4 _aEvolutionary Biology.
_939710
650 2 4 _aHuman Genetics.
_939711
650 2 4 _aBioinformatics.
_92365
650 2 4 _aMicrobial Genetics and Genomics.
_939712
650 2 4 _aAnimal Genetics and Genomics.
_939713
710 2 _aSpringerLink (Online service)
_94914
776 0 8 _iPrinted edition:
_z9783319540627
856 4 0 _uhttps://online.fliphtml5.com/lluzx/dzrh/
_zЦахимаар унших
942 _2ddc
_cEB
999 _c17744
_d17744